Modelling of malignant lymphoma in rabbits, using oncogenic viruses of non-human primates.
نویسندگان
چکیده
The discovery of lymphoid B-Iymphotropic herpesvirus-producing cell lines from M. arctoides peripheral lymphocytes (MAL-l) producing their own lymphotropic virus HVMA was reported earlier [1]. Subsequently, two more M. arctoides virus-producing lymphoid cell lines (MAL-2, MAL-3) were discovered in our laboratory. The cells of some baboon lymphoid cultures, parallel with B-Iymphotropic herpesvirus, produced C-type retrovirus antigenically similar to human T-Iymphotropic virus (HTLV)-1. The cells of MAL-1, MAL-2 and MAL-3 cultures also produced B-lymphotropic herpes-
منابع مشابه
Interaction of viral oncogenic proteins with the Wnt signaling pathway
It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenes...
متن کاملOncogenic Dna and Rna Viruses Causing the Cancer Pathogenesis
The present paper explore out the better-characterized and most intensively studied oncogenic viruses of humans and animals. Many DNA and RNA viruses have been proved to be oncogenic (or carcinogenic) in a variety of animals, ranging from amphibia to primates, and évidence grows stronger that certain forms of human cancer are of viral origin. Several DNA viruses have been associated with the ca...
متن کاملAnimal Models Utilized in HTLV-1 Research
Since the isolation and discovery of human T-cell leukemia virus type 1 (HTLV-1) over 30 years ago, researchers have utilized animal models to study HTLV-1 transmission, viral persistence, virus-elicited immune responses, and HTLV-1-associated disease development (ATL, HAM/TSP). Non-human primates, rabbits, rats, and mice have all been used to help understand HTLV-1 biology and disease progress...
متن کاملPRIMARY MALIGNANT LYMPHOMA OF THE BREAST
A case of primary malignant non-Hodgkin's lymphoma of the breast is reported. This is the first well-documented case of breast lymphoma in our institution and also in Iran. The diagnosis of primary breast lymphoma requires the presence of lymphomatous infiltration in close ass, tissue in patients with neither previous lymphoma nor concurrent lymphoma in another site. There is no definite cl...
متن کاملFailure to Demonstrate the Role of High Risk Human Papilloma Virus in Epithelial Ovarian Cancer
Background and Aims: Ovarian cancer is one of most common causes of cancer related women's mortalities. Human papilloma virus is a known factor concerning cervical cancer but its role in causing ovarian cancer is not yet verified. A few studies also identified HPV DNA in ovarian carcinoma tissues. However, some studies did not detect HPV DNA in ovarian carcinoma tissues. In this articl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Haematology and blood transfusion
دوره 31 شماره
صفحات -
تاریخ انتشار 1987